Hormones Part 1 | Medicinal Chemistry | Dr. Aqsa Murtaza
PHARMA BY AQSA MURTAZA (PharmD) Aim to help Pharmacy Students. We cover a wide range of topics, from Medicinal Chemistry, Pharmacology, and Drug Interactions to Medication Management and Disease State Management. MEDICINAL CHEMISTRY HORMONES Oxytocin Vasopressin Estrogen Progesterone Cortisol Glucagon Insulin Testosterone Aldosterone HORMONES The endocrine system is made up of the endocrine glands that secrete hormones. Chemical messenger Work slowly, over time, and controls many functions in our body. Hormones are carried by the blood throughout the entire body and affect specific cells. Metabolism, growth, etc. OXYTOCIN Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2 “Quick Birth” Induce labor Has 9-Amino acids, bound with a disulfide bridge Molecular formula = C43H66N12O12S2 Release from Posterior Pituitary Gland Given parenterally. ADR Severe uterine contraction Water retention Nasal irritation CONTRAINDICATION Uterine rupture Smooth muscle contracti...